The Search tab allows you to search for a text string in file titles, annotations, or leaf titles.
You can run a simple search directly from the search toolbar by entering a text string into the Look For: field.
Click the Find Now icon 
. The simple search will search all files, annotations, and titles by default.
When examining the results, choose the Locate icon 
to find the section within the Navigation pane where the document resides.
A more advanced search can be done by customizing a search query for better results. These searches can be saved for later use. To specify an advanced search, open the Search tab and click the Advanced icon 
. Then select the search conditions in the Advanced Search pane (highlighted with red box below).
Items are divided into search categories:
Files — Text of files in .pdf or Word, including file names
TOC Titles — Table of Contents as displayed in Navigation pane
Annotations — Annotations recorded on Annotations tab
File Reference Status — Current, Appended, Replaced, or Deleted
Reviewed — Yes or No
Module — Modules according to the CTD, plus orphaned files
When selecting multiple search conditions, all conditions must be met for results to be returned. For example, the conditions that a TOC Title must contain “lipids” and that the status must be Current will return only Current documents with the word “lipids” in the title.
When selecting search items, clicking on a parent section will select all subsections and child files automatically. For example, in the previous image, the Original Application and Efficacy Supplement “parents” are checked. Therefore, all files belonging to (i.e., children of) the Original Application and Efficacy Supplement will also be checked as shown in the image.
If some of the children are unchecked, the parent of that unchecked sequence will turn gray (for example, if 0001 Amendment was unchecked, 0000 Original Application would be gray).