The details of a contact in a United States eCTD 4.0 application can only be edited within the submission unit where it was originally created (i.e., the contact's status is “Created”).
In the Contacts tab, click the corresponding ... and select Edit.
The options are described in the “Create an application” section.
Contacts created in a past submission unit will appear in the Contacts tab with a status of “Created in [submission unit number]” and will not have the Edit option available. To modify a contact created in a previous submission, see “Update and undo update of a contact”.